27209 - Organic Chemistry I
Compulsory
5.1. Methodological overview
The methodology followed in this course is oriented towards achievement of the learning objectives. It favors the understanding of the different organic chemical processes. A wide range of teaching and learning tasks are implemented, such as theory sessions, assignments, and tutorials.
Students are expected to participate actively in the class throughout the course.
Classroom materials will be available via Moodle. These include a repository of the lecture notes used in class, the course syllabus, as well as other course-specific learning materials.
Further information regarding the course will be provided on the first day of class.
5.3. Syllabus
The course will address the following topics:
1. Properties and reactivity of alkanes and cycloalkanes: Free-radical halogenation.
2. Properties and reactivity of alkenes and alkynes: electrophilic addition reactions. Polymerization of alkenes.
3. Reactivity of pi-delocalized systems: allyl derivatives. Conjugated polyenes: Diels-Alder reaction.
4. Properties and reactions of haloalkanes: Reactions of nucleophilic substitution and elimination. Organometallic
reagents. Introduction to the retrosynthetic analysis.
5. Properties and reactivity of alcohols, ethers, epoxides and thioethers: Oxidations. Nucleophilic substitutions and
eliminations, rearrangements of carbocations, epoxide-opening reactions.
6. Properties and reactivity of amines and other nitrogen-derivatives: ammonium salts, diazonium salts, azo compounds.
7. Benzene and other aromatic compounds: electrophilic aromatic substitution.
8. Arenes, aryl halides, phenols and anilines: Influence of the benzene ring in the reactivity of the substituents. Aromatic
nucleophilic substitution.
9. Properties and reactivity of aldehydes and ketones: nucleophilic addition.
10. Properties and reactivity of carboxylic acids and their derivatives: nucleophilic acyl substitution.